Sperm Count 50% Lower in Men Whose Fathers Smoke, Says Study
While studies have repeatedly linked maternal smoking during pregnancy with reduced sperm count in male children, a new research showed that men whose fathers smoked at the time of pregnancy also had 50 per cent lower count of sperms than those with non-smoking fathers.
The findings showed that, independently of nicotine exposure from the mother, socioeconomic factors, and their own smoking, men with fathers who smoked had a 41 per cent lower sperm concentration and 51 per cent fewer sperm count than those with non-smoking fathers.
According to Jonatan Axelsson, Specialist Physician at Lund University in Sweden,
I was very surprised that regardless of the mother’s level of exposure to nicotine, the sperm count of men whose fathers smoked was so much lower. The father’s smoking is also linked to a shorter reproductive lifespan in daughters, so the notion that everything depends on whether the mother smokes or not doesn’t seem convincing.Jonatan Axelsson
However, the research has not determined the underlying mechanisms behind this. But, similar studies have shown links between smoking fathers and various health outcomes in children, such as malformations, Axelsson noted.
It could be because most newly occurring mutations (known as de novo mutations) come via the father and there are also links between the father's age and a number of complex diseases, said researchers in the paper published in the journal PLOS ONE.
In addition, researchers have observed that smoking is linked to DNA damage in sperm and that smokers have more breaks in the DNA strand.
Unlike the maternal ovum, the father’s gametes divide continuously throughout life and mutations often occur at the precise moment of cell division. We know that tobacco smoke contains many substances that cause mutations so one can imagine that, at the time of conception, the gametes have undergone mutations and thereby pass on genes that result in reduced sperm quality in the male offspring.Jonatan Axelsson
The study was conducted on 104 Swedish men aged between 17 and 20 years.
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