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How Does Diabetes Lead to Heart Failure?

How Does Diabetes Lead to Heart Failure?

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Heart problems are a common development for people with diabetes and now researchers have found that diabetes is an independent risk factor for the development of heart failure in the community-dwelling population.

According to health experts in India, if poorly controlled, diabetes leads to cardiomyopathy resulting in progressive deterioration of pumping capacity of heart.

"Due to myocardial infarction, the heart muscle becomes weak and eventually heart fails as a pump leading to congestive heart failure," Koul added.

According to the current study, published in the journal Mayo Clinic Proceedings, researchers evaluated the long-term impact of diabetes on the development of heart failure, both with preserved ejection fraction - a measurement of the percentage of blood leaving the heart with each contraction - and reduced ejection fraction.

They also looked at mortality in a community population, controlling for hypertension, coronary artery disease and diastolic function.

From an initial group of 2,042 residents of Olmsted County in US, 116 study participants with diabetes were matched 1:2 for age, hypertension, sex, coronary artery disease and diastolic dysfunction to 232 participants without diabetes.

Over the 10-year follow-up period, 21 per cent of participants with diabetes developed heart failure, independent of other causes.

In comparison, only 12 percent of patients without diabetes developed heart failure. Cardiac death, heart attack and stroke were not statistically different in the study between the two groups.

The study shows that diabetes is an independent risk factor for the development of heart failure in the community dwelling population.

Furthermore, the outcome data support the concept of a diabetic cardiomyopathy.

This research extends previous findings and demonstrates that even without a known cardiac structural abnormality and with a normal ejection fraction, diabetic patients are still at increased risk of developing heart failure as compared to their nondiabetic counterparts.

"Our hope is that this study provides a strong foundation for further investigations into diabetes and heart failure. There is still much to learn and study in terms of this association and how to best diagnose and treat this condition," Chen added.

(This story was auto-published from a syndicated feed. No part of the story has been edited by FIT .)

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