Diabetes Drug Could Treat Heart Disease: Study
Researchers have discovered that metformin, a drug commonly used to treat Type-2 diabetes, might also be used to treat a specific form of heart failure known as preserved ejection fraction (HFpEF), finds a new study.
In a mice study, published in the journal of General Physiology, researchers showed that metformin relaxes a key heart muscle protein called titin, allowing the heart to properly fill with blood before pumping it around the body. This improves the animals' capacity for exercise.
According to Henk Granzier, professor at the University of Arizona in the US,
HFpEF is more common in women and other risk factors include hypertension, old age, and obesity.
Unlike other forms of heart failure, however, there are currently no drugs available to treat HFpEF, according to the researchers.